Cognitive Development following Prenatal Cocaine-Exposure • 1235

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Cognitive outcomes of preschool children with prenatal cocaine exposure.

CONTEXT Because of methodological limitations, the results of the few prospective studies assessing long-term cognitive effects of prenatal cocaine exposure are inconsistent. OBJECTIVE To assess effects of prenatal cocaine exposure and quality of caregiving environment on 4-year cognitive outcomes. DESIGN Longitudinal, prospective, masked comparison cohort study from birth (September 1994-J...

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Overinhibition of corticostriatal activity following prenatal cocaine exposure.

OBJECTIVE Prenatal cocaine exposure (PCE) can cause persistent neuropsychological and motor abnormalities in affected children, but the physiological consequences of PCE remain unclear. Conclusions drawn from clinical studies can sometimes be confounded by polysubstance abuse and nutritional deprivation. However, existing observations suggest that cocaine exposure in utero, as in adults, increa...

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Growth, development, and behavior in early childhood following prenatal cocaine exposure: a systematic review.

CONTEXT Despite recent studies that failed to show catastrophic effects of prenatal cocaine exposure, popular attitudes and public policies still reflect the belief that cocaine is a uniquely dangerous teratogen. OBJECTIVE To critically review outcomes in early childhood after prenatal cocaine exposure in 5 domains: physical growth; cognition; language skills; motor skills; and behavior, atte...

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Systematic review of prenatal cocaine exposure and adolescent development.

BACKGROUND AND OBJECTIVE Previous research found that prenatal cocaine exposure (PCE) may increase children's vulnerability to behavior and cognition problems. Maturational changes in brain and social development make adolescence an ideal time to reexamine associations. The objective was to conduct a systematic review of published studies examining associations between PCE and adolescent develo...

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Systematic Review of Prenatal Cocaine Exposure and Adolescent Development abstract

BACKGROUND AND OBJECTIVE: Previous research found that prenatal cocaine exposure (PCE) may increase children’s vulnerability to behavior and cognition problems. Maturational changes in brain and social development make adolescence an ideal time to reexamine associations. The objective was to conduct a systematic review of published studies examining associations between PCE and adolescent devel...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1998

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-199804001-01256